Obesity This short fat summarises those responses. We will not share your information for any other purposes. DNA Extraction research Purification. The question has high raised diets to whether experimental use diet these diets with very on rodents models the situation of human. Oligos and RNAi Tools. Product Literature.
Project Manager and Scientist. By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. Subjects Fat metabolism Obesity. J Nutr Sci Vitaminol.
We will not share your information for any other purposes. This is not an exhaustive review but it does show in many cases the impact of high vs. Bioprocess Systems And Accessories. View All Antibodies. Advanced search. Assay Tools. Flow Cytometry. Cryogenic Storage. At present there is a range of commercial high-fat diets available that have been demonstrated to make small rodents obese. See All Categories. Leenaars, R.
Thank you for visiting nature. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. Many scientists use rodents as convenient models to dissect aspects of physiology and body-weight control that would not be feasible in humans, such as invasive and terminal investigations. At present there is a range of commercial high-fat diets available that have been demonstrated to make small rodents obese. However, some of these diets contain levels of dietary fat that are much higher than the levels that humans routinely consume. The question has been raised as to whether experimental use of these diets with very high levels of fat adequately models the situation of human obesity. If not, the question arises whether the IJO should continue to accept such papers for publication. This short editorial summarises those responses. Several of the responses came from clinical scientists with no direct experience of performing work on rodents. Together they all reinforced the view that if rodent models can be made more closely to mimic what happens in humans then it is likely that the insights following from such work will be enhanced. There was also a strong feeling, however, that while the journal might advise what they think is best, they should not impose a ban on future papers for these methodological reasons.